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Journal of Bacteriology, August 1999, p. 4719-4723, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Glucose Metabolism in gcr Mutants of Saccharomyces cerevisiae

H. Uemura1 and D. G. Fraenkel2,*

Section of Gene Engineering, Department of Molecular Biology, National Institute of Bioscience and Human Technology, Tsukuba-shi, 305 Japan,1 and Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 021152

Received 22 February 1999/Accepted 18 May 1999

A gcr2 null mutant of Saccharomyces cerevisiae grows well on glucose in spite of its lower level of glycolytic enzymes between triose phosphates and pyruvate. A quantitative analysis shows that these levels are adequate to the flux but glycerate phosphates are elevated.

* Corresponding author. Mailing address: Microbiology and Molecular Genetics, Bldg. D1-121, Harvard Medical School, 200 Longwood Ave., Boston, MA 02115. Phone: (617) 432-1912. Fax: (617) 738-7664. E-mail: fraenkel{at}hms.harvard.edu.

Journal of Bacteriology, August 1999, p. 4719-4723, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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