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Journal of Bacteriology, August 1999, p. 5123-5125, Vol. 181, No. 16
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Escherichia coli Gene ydeA Encodes a Major Facilitator Pump Which Exports L-Arabinose and Isopropyl-beta -D-Thiogalactopyranoside

Sandra Carolé, Sébastien Pichoff,dagger and Jean-Pierre Bouché*

Laboratoire de Microbiologie et de Génétique Moléculaire du CNRS, 31062 Toulouse, France

Received 18 February 1999/Accepted 4 June 1999

Inactivation of the Escherichia coli gene ydeA, which encodes a member of the major facilitator superfamily, decreased the efflux of L-arabinose, thereby affecting the expression of AraC-regulated genes. In addition, overexpression of ydeA decreased the expression of genes regulated by isopropyl-beta -D-thiogalactopyranoside.

* Corresponding author. Mailing address: Laboratoire de Microbiologie et de Génétique Moléculaire du CNRS, 118 Route de Narbonne, 31062 Toulouse, France. Phone: (33)-561-335-961. Fax: (33)-661-335-886. E-mail: jpbouche{at}ibcg.biotoul.fr.

dagger Present address: Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160-7420.

Journal of Bacteriology, August 1999, p. 5123-5125, Vol. 181, No. 16
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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