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Journal of Bacteriology, October 1999, p. 6179-6183, Vol. 181, No. 19
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Chromosome Segregation and Cell Division Defects in recBC sbcBC ruvC Mutants of Escherichia coli

Davor Zahradka,* Ksenija Vlahovic', Mirjana Petranovic', and Drago Petranovic'dagger

Department of Molecular Genetics, Ruđer Boskovic' Institute, 10001 Zagreb, Croatia

Received 8 March 1999/Accepted 28 July 1999

The RuvC protein is important for DNA recombination and repair in Escherichia coli. The present work shows that a ruvC null mutation introduced into a recBC sbcBC background causes severe defects in chromosome segregation and cell division. Both defects were found to result from abortive recombination initiated by the RecA protein.

* Corresponding author. Mailing address: Department of Molecular Genetics, Ruđer Boskovic' Institute, Bijenicka 54, P.O. Box 1016, 10001 Zagreb, Croatia. Phone: 385-1-4560-971. Fax: 385-1-4561-177. E-mail: zahradka{at}rudjer.irb.hr.

dagger Drago-Dadi Petranovic' passed away on 19 July 1998. His dedication to scientific work and his enthusiasm will stay as permanent inspiration for all of us.

Journal of Bacteriology, October 1999, p. 6179-6183, Vol. 181, No. 19
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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