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Journal of Bacteriology, January 1999, p. 675-680, Vol. 181, No. 2
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Identification of SycN, YscX, and YscY, Three New Elements of the Yersinia Yop Virulon

Maite Iriarte and Guy R. Cornelis*

Microbial Pathogenesis Unit, Christian de Duve Institute of Cellular Pathology and Faculté de Médecine, Université Catholique de Louvain, B-1200 Brussels, Belgium

Received 4 August 1998/Accepted 28 October 1998

The Yop virulon allows Yersinia spp. to resist the immune response of the host by injecting harmful proteins into host cells. We identified three new elements of the Yop virulon: SycN, required for normal secretion of YopN, and YscX and YscY, two new components of the secretion machinery.


* Corresponding author. Mailing address: Microbial Pathogenesis Unit, Université de Louvain, Avenue Hippocrate, 74, UCL 74.49, B-1200 Brussels, Belgium. Phone: 32 2 764 74 49. Fax: 32 2 764 74 98. E-mail: cornelis{at}mipa.ucl.ac.be.


Journal of Bacteriology, January 1999, p. 675-680, Vol. 181, No. 2
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.



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