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Journal of Bacteriology, October 1999, p. 6556-6559, Vol. 181, No. 20
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

A Novel Gene Required for Rhamnose-Glucose Polysaccharide Synthesis in Streptococcus mutans

Yoshihisa Yamashita,1,* Yukie Shibata,1 Yoshio Nakano,1 Hiromasa Tsuda,1 Nobuo Kido,2 Michio Ohta,3 and Toshihiko Koga1

Department of Preventive Dentistry, Kyushu University Faculty of Dentistry, Fukuoka 812-8582,1 Biosystems, School of Informatics and Sciences, Nagoya University, Nagoya 464-8601,2 and Department of Bacteriology, Nagoya University, School of Medicine, Nagoya 466-8550,3 Japan

Received 7 June 1999/Accepted 30 July 1999

Gene rgpG is required for biosynthesis of rhamnose-glucose polysaccharide (RGP) in Streptococcus mutans. Its deduced amino acid sequence had similarity to WecA, which initiates syntheses of enterobacterial common antigen and some O antigens in Escherichia coli. Gene rgpG complemented a wecA mutation of E. coli, suggesting that rgpG may function similarly in RGP synthesis.

* Corresponding author. Mailing address: Department of Preventive Dentistry, Kyushu University Faculty of Dentistry, Fukuoka 812-8582, Japan. Phone: 81-92-642-6353. Fax: 81-92-642-6354. E-mail: yoshidha{at}mbox.nc.kyushu-u.ac.jp.

Journal of Bacteriology, October 1999, p. 6556-6559, Vol. 181, No. 20
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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