Journal of Bacteriology, April 1999, p. 2261-2266, Vol. 181, No. 7
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
Departments of Medicine and Microbiology and
Immunology,
Received 29 September 1998/Accepted 20 January 1999
Analysis of 12 Helicobacter pylori promoters indicates
the existence of a consensus
10 hexamer (TAtaaT) but
little conservation of
35 sequences. In this study, mutations in
either the H. pylori vacA
10 region or the
35 region
resulted in decreased vacA transcription and suggested that
an extended
10 motif is utilized. Thus, despite the lack of a
35
consensus sequence for H. pylori promoters, the
35 region
plays a functional role in vacA transcription.
*
Corresponding author. Mailing address: Division of
Infectious Diseases, A3310 Medical Center North, Vanderbilt University School of Medicine, Nashville TN 37232-2605. Phone: (615) 322-2035. Fax: (615) 343-6160.
This article has been cited by other articles:
| Appl. Environ. Microbiol. | Infect. Immun. | Eukaryot. Cell |
|---|---|---|
| Mol. Cell. Biol. | J. Virol. | Microbiol. Mol. Biol. Rev. |
| ALL ASM JOURNALS |