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Journal of Bacteriology, October 2000, p. 5922-5924, Vol. 182, No. 20
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

No Genetic Barriers between Salmonella enterica Serovar Typhimurium and Escherichia coli in SOS-Induced Mismatch Repair-Deficient Cells

Ivan Matic,* François Taddei, and Miroslav Radman

E9916 INSERM, Faculté de Médecine---"Necker---Enfants malades," Université René Descartes, 75015 Paris, France

Received 15 May 2000/Accepted 6 July 2000

Conjugational crosses trigger SOS induction in Escherichia coli F- cells mated with Salmonella enterica serovar Typhimurium Hfr donors. Using an epigenetic indicator of SOS induction, we showed that a strong SOS response occurring in a subpopulation of mated mismatch repair-deficient cells totally abolishes genetic barriers between these two genera.

* Corresponding author. Mailing address: E9916 INSERM, Faculté de Médecine---"Necker---Enfants malades," Université Rene Descartes-Paris V, 156 Rue de Vaugirard, 75730 Paris Cedex 15, France. Phone: (33) 1 40 61 53 21. Fax: (33) 1 40 61 53 22. E-mail: matic{at}necker.fr.

Journal of Bacteriology, October 2000, p. 5922-5924, Vol. 182, No. 20
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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