This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hunke, S.
Right arrow Articles by Schneider, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hunke, S.
Right arrow Articles by Schneider, E.

 Previous Article  |  Next Article 

Journal of Bacteriology, March 2000, p. 1432-1436, Vol. 182, No. 5
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Novel Missense Mutations That Affect the Transport Function of MalK, the ATP-Binding-Cassette Subunit of the Salmonella enterica Serovar Typhimurium Maltose Transport System

Sabine Hunke, Heidi Landmesser, and Erwin Schneider*

Institut für Biologie/Bakterienphysiologie, Humboldt-Universität zu Berlin, D-10099 Berlin, Germany

Received 11 August 1999/Accepted 8 December 1999

We report on novel mutations in the malK gene of Salmonella enterica serovar Typhimurium, encoding the ATPase subunit of the maltose transporter (MalFGK2). Biochemical analysis suggests that (i) L86 might be involved in a signaling step during substrate translocation and (ii) E306 may be critical for the structural integrity of the protein.

* Corresponding author. Mailing address: Humboldt-Universität zu Berlin, Institut für Biologie/Bakterienphysiologie, Chausseestr. 117, D-10115 Berlin, Germany. Phone: 49 (0)30-2093-8121. Fax: 49 (0)30-2093-8126. E-mail: erwin.schneider{at}rz.hu-berlin.de.

Journal of Bacteriology, March 2000, p. 1432-1436, Vol. 182, No. 5
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Davidson, A. L., Dassa, E., Orelle, C., Chen, J. (2008). Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems. Microbiol. Mol. Biol. Rev. 72: 317-364 [Abstract] [Full Text]  
  • Daus, M. L., Landmesser, H., Schlosser, A., Muller, P., Herrmann, A., Schneider, E. (2006). ATP Induces Conformational Changes of Periplasmic Loop Regions of the Maltose ATP-binding Cassette Transporter. J. Biol. Chem. 281: 3856-3865 [Abstract] [Full Text]  
  • Lau, G. H. Y., MacGillivray, R. T. A., Murphy, M. E. P. (2004). Characterization of a Nucleotide-Binding Domain Associated with Neisserial Iron Transport. J. Bacteriol. 186: 3266-3269 [Abstract] [Full Text]  
  • Kashiwagi, K., Innami, A., Zenda, R., Tomitori, H., Igarashi, K. (2002). The ATPase Activity and the Functional Domain of PotA, a Component of the Spermidine-preferential Uptake System in Escherichia coli. J. Biol. Chem. 277: 24212-24219 [Abstract] [Full Text]  
  • Hunke, S., Mourez, M., Jehanno, M., Dassa, E., Schneider, E. (2000). ATP Modulates Subunit-Subunit Interactions in an ATP-binding Cassette Transporter (MalFGK2) Determined by Site-directed Chemical Cross-linking. J. Biol. Chem. 275: 15526-15534 [Abstract] [Full Text]  
  • Bohm, A., Diez, J., Diederichs, K., Welte, W., Boos, W. (2002). Structural Model of MalK, the ABC Subunit of the Maltose Transporter of Escherichia coli. IMPLICATIONS FOR mal GENE REGULATION, INDUCER EXCLUSION, AND SUBUNIT ASSEMBLY. J. Biol. Chem. 277: 3708-3717 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»