Multiple Alleles of Treponema pallidum Repeat Gene D in Treponema pallidum Isolates

doi:10.1128/JB.182.8.2332-2335.2000

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Journal of Bacteriology, April 2000, p. 2332-2335, Vol. 182, No. 8
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Multiple Alleles of Treponema pallidum Repeat Gene D in Treponema pallidum Isolates

Arturo Centurion-Lara, Eileen S. Sun, Lynn K. Barrett, Christa Castro, Sheila A. Lukehart, and Wesley C. Van Voorhis^*

Departments of Medicine and Pathobiology, University of Washington, Seattle, Washington 98195-7185

Received 20 September 1999/Accepted 5 January 2000

Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolatesand 7 of 8 non-pallidum isolates, and tprD3 is found in one T.pallidum subsp. pertenue isolate. Antibodies against TprD2 arefound in persons with syphilis, demonstrating that tprD2 is expressedduringinfection.

^* Corresponding author. Mailing address: Departments of Medicine and Pathobiology, University of Washington, Box 357185, Seattle,WA 98195-7185. Phone: (206) 543-0821. Fax: (206) 685-8681. E-mail:wesley{at}u.washington.edu.

Journal of Bacteriology, April 2000, p. 2332-2335, Vol. 182, No. 8
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

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