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Journal of Bacteriology, April 2000, p. 2341-2344, Vol. 182, No. 8
Institute for Animal Health, Compton,
Berkshire RG20 7NN, United Kingdom,1 and
Indian Veterinary Research Institute, Izatnagar, Bareilly
243122, India2
Received 12 November 1999/Accepted 31 January 2000
Type III secreted Sop protein effectors are delivered into target
eukaryotic cells and elicit cellular responses underlying Salmonella pathogenicity. In this work, we have identified
another secreted protein, SopE2, and showed that SopE2 is an important invasion-associated effector. SopE2 is encoded by the sopE2
gene which is present and conserved in pathogenic strains of
Salmonella. SopE2 is highly homologous to SopE, a protein
encoded by a gene within a temperate bacteriophage and present in only
some pathogenic strains.
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Identification of SopE2, a Salmonella
Secreted Protein Which Is Highly Homologous to SopE and Involved in
Bacterial Invasion of Epithelial Cells
*
Corresponding author. Mailing address: Institute for
Animal Health, Compton, Berkshire RG20 7NN, United Kingdom. Phone: (44) 1635 577291. Fax: (44) 1635 577243. E-mail:
edouard.galyov{at}bbsrc.ac.uk.
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