JB
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhao, J.
Right arrow Articles by Winkler, M. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhao, J.
Right arrow Articles by Winkler, M. E.

Journal of Bacteriology, March 2001, p. 1796-1800, Vol. 183, No. 5
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.5.1796-1800.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

The miaA Mutator Phenotype of Escherichia coli K-12 Requires Recombination Functions

Jingyong Zhao, Hon-Chiu Eastwood Leung, and Malcolm E. Winkler*

Department of Microbiology and Molecular Genetics, University of Texas---Houston Medical School, Houston, Texas 77030

Received 3 October 2000/Accepted 4 December 2000

miaA mutants, which contain A-37 instead of the ms2i6A-37 hypermodification in their tRNA, show a moderate mutator phenotype leading to increased GCright-arrowTA transversion. We show that the miaA mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those required for translation stress-induced mutagenesis.

* Corresponding author. Present address: Lilly Research Laboratories, Drop Code 1543, Indianapolis, IN 46285. Phone: (317) 433-0095. Fax: (317) 276-9159. E-mail: Winkler_Malcolm_E{at}Lilly.com.

Journal of Bacteriology, March 2001, p. 1796-1800, Vol. 183, No. 5
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.5.1796-1800.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
Mol. Cell. Biol. J. Virol. Microbiol. Mol. Biol. Rev.
ALL ASM JOURNALS

Copyright © 2001 by the American Society for Microbiology. All rights reserved.