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Journal of Bacteriology, March 2001, p. 1830-1834, Vol. 183, No. 5
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.5.1830-1834.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

VibD and VibH Are Required for Late Steps in Vibriobactin Biosynthesis in Vibrio cholerae

Elizabeth E. Wyckoff,* Stacey L. Smith, and Shelley M. Payne

Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712-1095

Received 11 October 2000/Accepted 7 December 2000

Vibrio cholerae synthesizes the catechol siderophore vibriobactin. In this report, we present the complete map of a vibriobactin gene region containing two previously unreported vibriobactin biosynthetic genes. vibD encodes a phosphopantetheinyl transferase, and vibH encodes a novel nonribosomal peptide synthase. Both VibD and VibH are required for vibriobactin biosynthesis.

* Corresponding author. Mailing address: Section of Molecular Genetics and Microbiology, University of Texas, Austin, TX 78712-1095. Phone: (512) 471-5204. Fax: (512) 471-7088. E-mail: ewyckoff{at}mail.utexas.edu.

Journal of Bacteriology, March 2001, p. 1830-1834, Vol. 183, No. 5
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.5.1830-1834.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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