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Journal of Bacteriology, July 2002, p. 3759-3764, Vol. 184, No. 13
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.13.3759-3764.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

The Enigmatic Escherichia coli fadE Gene Is yafH

John W. Campbell1 and John E. Cronan Jr.1,2*

Departments of Microbiology,1 Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 618012

Received 25 February 2002/ Accepted 8 April 2002

The identity of the gene encoding acyl coenzyme A dehydrogenase is a major remaining mystery of the Escherichia coli fatty acid degradation (fad) regulon. Our prior genome array analyses showed that transcription of the yafH gene is controlled by the FadR regulatory protein. We now report direct experimental proof that yafH and fadE are the same gene.

* Corresponding author. Mailing address: Department of Microbiology, University of Illinois, B103 Chemical and Life Sciences Laboratory, 601 S. Goodwin Ave., Urbana, IL 61801. Phone: (217) 333-7919. Fax: (217) 244-6697. E mail: j-cronan{at}life.uiuc.edu.

Journal of Bacteriology, July 2002, p. 3759-3764, Vol. 184, No. 13
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.13.3759-3764.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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