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Journal of Bacteriology, February 2002, p. 859-860, Vol. 184, No. 3
0021-9193/01/$04.00+0     DOI: 10.1128/JB.184.3.859-860.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Integrative Genetic Element That Reverses the Usual Target Gene Orientation

Sihui Zhao and Kelly P. Williams*

Department of Biology, Indiana University, Bloomington, Indiana 47405

Received 2 August 2001/ Accepted 1 November 2001

A genetic element integrating site specifically into a prokaryotic gene usually carries a copy of the 3' portion of that gene that restores the active gene even as the original is disrupted. A cryptic element in Mesorhizobium loti instead carries a copy of the 5' end of the tRNA gene into which it integrated. This has implications for the evolution of new integrase-site combinations.

* Corresponding author. Mailing address: 1001 East Third St., Bloomington IN 47405. Phone: (812) 856-5697. Fax: (812) 855-6705. E-mail: kwilliam{at}bio.indiana.edu.

Journal of Bacteriology, February 2002, p. 859-860, Vol. 184, No. 3
0021-9193/01/$04.00+0     DOI: 10.1128/JB.184.3.859-860.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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  • Boltner, D., MacMahon, C., Pembroke, J. T., Strike, P., Osborn, A. M. (2002). R391: a Conjugative Integrating Mosaic Comprised of Phage, Plasmid, and Transposon Elements. J. Bacteriol. 184: 5158-5169 [Abstract] [Full Text]  


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