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Journal of Bacteriology, March 2002, p. 1767-1771, Vol. 184, No. 6
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.6.1767-1771.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Analyses of the Roles of the Three cheA Homologs in Chemotaxis of Vibrio cholerae

Khoosheh K. Gosink,1 Reiji Kobayashi,2 Ikuro Kawagishi,2 and Claudia C. Häse1*

Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105,1 Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan2

Received 31 October 2001/ Accepted 11 December 2001

The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.


* Corresponding author. Mailing address: Infectious Diseases, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105. Phone: (901) 495-2865. Fax: (901) 495-3099. E-mail: claudia.hase{at}stjude.org.


Journal of Bacteriology, March 2002, p. 1767-1771, Vol. 184, No. 6
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.6.1767-1771.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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