This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Takamatsu, D.
Right arrow Articles by Sekizaki, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Takamatsu, D.
Right arrow Articles by Sekizaki, T.

 Previous Article  |  Next Article 

Journal of Bacteriology, April 2002, p. 2050-2057, Vol. 184, No. 7
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.7.2050-2057.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Evidence for Lateral Transfer of the Suilysin Gene Region of Streptococcus suis

Daisuke Takamatsu, Makoto Osaki, and Tsutomu Sekizaki*

National Institute of Animal Health, Tsukuba, Ibaraki, Japan

Received 24 September 2001/ Accepted 3 January 2002

Suilysin is a cholesterol-binding cytolysin encoded by sly in Streptococcus suis. DNA sequence determination of the sly locus in a strain lacking sly revealed the presence of another gene, designated orf102, in the place of sly. No transposable element or long-repeat sequence was found in the close vicinity. Except for six strains whose corresponding loci have been rearranged, all of the remaining 62 strains examined had either sly or orf102 at the same locus and their flanking regions were conserved. The genetic organizations having either sly or orf102 were found in the strains whose 16S rRNA sequences were identical. These results suggest that S. suis acquired sly or orf102 from a foreign source and that these genes subsequently spread among S. suis strains by homologous recombination.

* Corresponding author. Mailing address: Molecular Bacteriology Section, National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan. Phone: 81 (298) 38-7743. Fax: 81 (298) 38-7907. E-mail: sekizaki{at}affrc.go.jp.

Journal of Bacteriology, April 2002, p. 2050-2057, Vol. 184, No. 7
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.7.2050-2057.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Dumetz, F., Duchaud, E., Claverol, S., Orieux, N., Papillon, S., Lapaillerie, D., Le Henaff, M. (2008). Analysis of the Flavobacterium psychrophilum outer-membrane subproteome and identification of new antigenic targets for vaccine by immunomics. Microbiology 154: 1793-1801 [Abstract] [Full Text]  
  • Sekizaki, T., Takamatsu, D., Osaki, M., Shimoji, Y. (2005). Different Foreign Genes Incidentally Integrated into the Same Locus of the Streptococcus suis Genome. J. Bacteriol. 187: 872-883 [Abstract] [Full Text]  
  • Harel, J., Martinez, G., Nassar, A., Dezfulian, H., Labrie, S. J., Brousseau, R., Moineau, S., Gottschalk, M. (2003). Identification of an Inducible Bacteriophage in a Virulent Strain of Streptococcus suis Serotype 2. Infect. Immun. 71: 6104-6108 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»