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Journal of Bacteriology, January 2003, p. 371-373, Vol. 185, No. 1
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.1.371-373.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Choline Starvation Induces the Gene licD2 in Streptococcus pneumoniae

Bhushan V. Desai,1 Harvard Reiter,2 and Donald A. Morrison1*

Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607,1 Cell Controls Corporation, Chicago, Illinois2

Received 13 June 2002/ Accepted 8 October 2002

Mutant strains of Streptococcus pneumoniae were constructed to monitor the regulation of three dispersed genes known or predicted to act in choline metabolism. One gene (licD2) was regulated in response to choline deprivation over a 30-fold range. The other two (SP1860 and licC) responded little if at all to the same challenge.

* Corresponding author. Mailing address: Laboratory for Molecular Biology (M/C 567), University of Illinois at Chicago, 900 S. Ashland Ave., Chicago, IL 60607. Phone: (312) 996 6839. Fax: (312) 413 2691. E-mail: DAMorris{at}uic.edu.

Journal of Bacteriology, January 2003, p. 371-373, Vol. 185, No. 1
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.1.371-373.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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