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Journal of Bacteriology, August 2003, p. 4997-5002, Vol. 185, No. 16
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.16.4997-5002.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Identification of Long Intergenic Repeat Sequences Associated with DNA Methylation Sites in Caulobacter crescentus and Other {alpha}-Proteobacteria

Swaine L. Chen and Lucy Shapiro*

Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94304-5329

Received 18 March 2003/ Accepted 14 May 2003

A systematic search for motifs associated with CcrM DNA methylation sites revealed four long (>100-bp) motifs (CIR sequences) present in up to 21 copies in Caulobacter crescentus. The CIR1 and CIR2 motifs exhibit a conserved inverted repeat organization, with a CcrM site in the center of one of the repeats.

* Corresponding author. Mailing address: Department of Developmental Biology, Stanford University School of Medicine, Beckman Center, B300, 279 Campus Dr., Stanford, CA 94304-5329. Phone: (650) 725-7678. Fax: (650) 725-7739. E-mail: shapiro{at}cmgm.stanford.edu.

Journal of Bacteriology, August 2003, p. 4997-5002, Vol. 185, No. 16
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.16.4997-5002.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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