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Regulation of fur Expression by RpoS and Fur in Vibrio vulnificus

Department of Environmental Science, Hankuk University of Foreign StudiesYongin,¹ Proteome Analysis Laboratory, KRIBB, Daejeon,² Department of Parasitology and Institute of Tropical Medicine, Yonsei University School of Medicine, Seoul, Korea³

Received 24 March 2003/ Accepted 7 July 2003

In a proteomic analysis of rpoS-deficient Vibrio vulnificus versus the wild type, one of the down-regulated proteins in the rpoS mutant strain was identified as a Fur protein, a ferric uptake regulator. The expression of a fur::luxAB fusion was significantly influenced by sigma factor S, the rpoS gene product, and positively regulated by Fur under iron-limited conditions.

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