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Journal of Bacteriology, March 2003, p. 2046-2050, Vol. 185, No. 6
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.6.2046-2050.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Identification of an Unknown Promoter, OUTIIp, within the IS10R Element

Esteban Martínez-García, Juana María Navarro-Lloréns, and Antonio Tormo*

Departamento de Bioquímica y Biología Molecular I, Universidad Complutense de Madrid, 28040 Madrid, Spain

Received 16 September 2002/ Accepted 14 December 2002

A novel promoter in IS10R (OUTIIp) has been found in one of its ends in an inverted position relative to promoter pOUT. OUTIIp shows characteristics similar to those of rpoS-dependent promoters such as a gearbox expression pattern. It is under catabolite repression and positively regulated by ppGpp or conditioned media. This opens new challenges in IS10R transposition.

* Corresponding author. Mailing address: Departamento de Bioquímica y Biología Molecular I, Facultad de Biología, Universidad Complutense de Madrid, 28040 Madrid, Spain. Phone: (34)-91-394-4156. Fax: (34)-91-394-4672. E-mail: tormo{at}bbm1.ucm.es.

Journal of Bacteriology, March 2003, p. 2046-2050, Vol. 185, No. 6
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.6.2046-2050.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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