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Journal of Bacteriology, May 2004, p. 3249-3253, Vol. 186, No. 10
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.10.3249-3253.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Contribution of the RpoA C-Terminal Domain to Stimulation of the Salmonella enterica hilA Promoter by HilC and HilD

Igor N. Olekhnovich and Robert J. Kadner*

Department of Microbiology, University of Virginia School of Medicine, Charlottesville, Virginia 22908-0734

Received 7 October 2003/ Accepted 29 January 2004

Expression of invasion genes in Salmonella pathogenicity island 1 (SPI-1) is mainly driven by the transcriptional activator HilA. Transcription of hilA is subject to complex control and is stimulated by the SPI-1-encoded HilC and HilD proteins. The C-terminal domain of RpoA contributes to hilA activation by HilC/D under certain inducing conditions.

* Corresponding author. Mailing address: Department of Microbiology, University of Virginia, P.O. Box 800734, Charlottesville, VA 22908-0734. Phone: (434) 924-2532. Fax: (434) 982-1071. E-mail: rjk{at}virginia.edu.

Journal of Bacteriology, May 2004, p. 3249-3253, Vol. 186, No. 10
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.10.3249-3253.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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