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Journal of Bacteriology, July 2004, p. 4395-4398, Vol. 186, No. 13
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.13.4395-4398.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Characterization of Tn916S, a Tn916-Like Element Containing the Tetracycline Resistance Determinant tet(S)

Holli Lancaster,1 Adam P. Roberts,1 Raman Bedi,2 Michael Wilson,1 and Peter Mullany1*

Division of Infection and Immunity, Eastman Dental Institute for Oral Health Care Sciences, University College London, London WC1X 8LD,1 Department of Health, London SE1 8UG, United Kingdom2

Received 26 January 2004/ Accepted 23 March 2004

We have characterized a transferable tetracycline resistance (Tcr) element from a Streptococcus intermedius isolate. The gene responsible for this resistance was identified by PCR and Southern hybridization as tet(S). Furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to Tn916. This element has been designated Tn916S.

* Corresponding author. Mailing address: Division of Infection and Immunity, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Gray's Inn Rd., London WC1X 8LD, United Kingdom. Phone: 020 7915 1050. Fax: 020 7915 1127. E-mail: pmullany{at}eastman.ucl.ac.uk.

Journal of Bacteriology, July 2004, p. 4395-4398, Vol. 186, No. 13
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.13.4395-4398.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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