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Journal of Bacteriology, July 2004, p. 4395-4398, Vol. 186, No. 13
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.13.4395-4398.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Characterization of Tn916S, a Tn916-Like Element Containing the Tetracycline Resistance Determinant tet(S)

Division of Infection and Immunity, Eastman Dental Institute for Oral Health Care Sciences, University College London, London WC1X 8LD,¹ Department of Health, London SE1 8UG, United Kingdom²

Received 26 January 2004/ Accepted 23 March 2004

We have characterized a transferable tetracycline resistance (Tc^r) element from a Streptococcus intermedius isolate. The gene responsible for this resistance was identified by PCR and Southern hybridization as tet(S). Furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to Tn916. This element has been designated Tn916S.

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