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Journal of Bacteriology, January 2004, p. 566-569, Vol. 186, No. 2
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.2.566-569.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Surface Layer Protein EA1 Is Not a Component of Bacillus anthracis Spores but Is a Persistent Contaminant in Spore Preparations

Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294

Received 25 August 2003/ Accepted 16 October 2003

EA1 is an abundant, highly antigenic, surface layer protein of Bacillus anthracis vegetative cells. Recent studies indicate that EA1 is also a component of B. anthracis spores and a potential marker for spore detection. We show here that EA1 is not a spore component but a persistent contaminant in spore preparations.

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