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Journal of Bacteriology, March 2004, p. 1902-1904, Vol. 186, No. 6
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.6.1902-1904.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Analysis of an Agmatine Deiminase Gene Cluster in Streptococcus mutans UA159

Department of Oral Biology, University of Florida, Gainesville, Florida

Received 19 September 2003/ Accepted 3 December 2003

An operon encoding enzymes of the agmatine deiminase system (AgDS) has been identified in the cariogenic bacterium Streptococcus mutans UA159. The AgDS is regulated by agmatine induction and carbohydrate catabolite repression. Ammonia is produced from agmatine at low pH, suggesting that the AgDS could augment acid tolerance.

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