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Journal of Bacteriology, April 2004, p. 2221-2223, Vol. 186, No. 7
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.7.2221-2223.2003
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Compartmentalization of Gene Expression during Sporulation of Bacillus subtilis Is Compromised in Mutants Blocked at Stage III of Sporulation

Zusheng Li,{dagger} Francis Di Donato, and Patrick J. Piggot*

Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania

Received 30 October 2003/ Accepted 23 December 2003

Mutations in the spoIIIA and spoIIIJ loci disrupt the compartmentalization of gene expression during sporulation of Bacillus subtilis. The breakdown in compartmentalization is not the cause of their being blocked in spore formation. Rather, it appears to be a consequence of the engulfed prespore's being unstable.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Temple University School of Medicine, 3400 N. Broad St., Philadelphia, PA 19140. Phone: (215) 707-7927. Fax: (215) 707-7788. E-mail: piggotp{at}temple.edu.

{dagger} Present address: Fox Chase Cancer Center, Philadelphia, PA 19111.

Journal of Bacteriology, April 2004, p. 2221-2223, Vol. 186, No. 7
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.7.2221-2223.2003
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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