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Natural Isolates of Salmonella enterica Serovar Dublin Carry a Single nadA Missense Mutation

Ulfar Bergthorsson and John R. Roth^*

Department of Biology, University of Utah, Salt Lake City, Utah

Received 1 August 2004/ Accepted 28 September 2004

Nicotinic acid is required by most isolates of Salmonella enterica (serovar Dublin), a pathogen of cattle. A single nadA missense mutation causes the nutritional requirement of all serovar Dublin isolates tested. Models for persistence of this allele are tested and discussed.

Present address: Department of Biology, Indiana University, Bloomington, IN 47405.

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