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Journal of Bacteriology, July 2005, p. 5023-5028, Vol. 187, No. 14
0021-9193/05/$08.00+0 doi:10.1128/JB.187.14.5023-5028.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, P.O. Box 56, Dunedin, New Zealand
Received 26 January 2005/ Accepted 13 April 2005
The F1Fo-ATP synthase plays an important role in a number of vital cellular processes in plants, animals, and microorganisms. In this study, we constructed a
atpD mutant of Mycobacterium smegmatis and demonstrated that atpD encoding the ß subunit of the F1Fo-ATP synthase is an essential gene in M. smegmatis during growth on nonfermentable and fermentable carbon sources.
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