This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hale, J. D. F. Articles by Tagg, J. R. Search for Related Content PubMed PubMed Citation Articles by Hale, J. D. F. Articles by Tagg, J. R.

Identification of nlmTE, the Locus Encoding the ABC Transport System Required for Export of Nonlantibiotic Mutacins in Streptococcus mutans

Department of Microbiology and Immunology, University of Otago, P.O. Box 56, Dunedin, New Zealand

Received 17 December 2004/ Accepted 18 April 2005

Streptococcus mutans UA159, the genome sequence reference strain, exhibits nonlantibiotic bacteriocin (mutacin) activity. In this study, we have combined bioinformatic and mutational analyses to identify the ABC transporter designated NlmTE, which is required for mutacin biogenesis in strain UA159 as well as in another mutacin producer, S. mutans N.

This article has been cited by other articles:

• Chong, P., Drake, L., Biswas, I. (2008). LiaS Regulates Virulence Factor Expression in Streptococcus mutans. Infect. Immun. 76: 3093-3099 [Abstract] [Full Text]  
• Kamiya, R. U., Hofling, J. F., Goncalves, R. B. (2008). Frequency and expression of mutacin biosynthesis genes in isolates of Streptococcus mutans with different mutacin-producing phenotypes. J Med Microbiol 57: 626-635 [Abstract] [Full Text]  
• Sztajer, H., Lemme, A., Vilchez, R., Schulz, S., Geffers, R., Yip, C. Y. Y., Levesque, C. M., Cvitkovitch, D. G., Wagner-Dobler, I. (2008). Autoinducer-2-Regulated Genes in Streptococcus mutans UA159 and Global Metabolic Effect of the luxS Mutation. J. Bacteriol. 190: 401-415 [Abstract] [Full Text]  
• Vickerman, M. M., Iobst, S., Jesionowski, A. M., Gill, S. R. (2007). Genome-Wide Transcriptional Changes in Streptococcus gordonii in Response to Competence Signaling Peptide. J. Bacteriol. 189: 7799-7807 [Abstract] [Full Text]  
• Robson, C. L., Wescombe, P. A., Klesse, N. A., Tagg, J. R. (2007). Isolation and partial characterization of the Streptococcus mutans type AII lantibiotic mutacin K8. Microbiology 153: 1631-1641 [Abstract] [Full Text]  
• Heng, N. C. K., Tagg, J. R., Tompkins, G. R. (2007). Competence-Dependent Bacteriocin Production by Streptococcus gordonii DL1 (Challis). J. Bacteriol. 189: 1468-1472 [Abstract] [Full Text]  
• Heng, N. C. K., Ragland, N. L., Swe, P. M., Baird, H. J., Inglis, M. A., Tagg, J. R., Jack, R. W. (2006). Dysgalacticin: a novel, plasmid-encoded antimicrobial protein (bacteriocin) produced by Streptococcus dysgalactiae subsp. equisimilis. Microbiology 152: 1991-2001 [Abstract] [Full Text]  
• Hale, J. D. F., Ting, Y.-T., Jack, R. W., Tagg, J. R., Heng, N. C. K. (2005). Bacteriocin (Mutacin) Production by Streptococcus mutans Genome Sequence Reference Strain UA159: Elucidation of the Antimicrobial Repertoire by Genetic Dissection. Appl. Environ. Microbiol. 71: 7613-7617 [Abstract] [Full Text]