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Journal of Bacteriology, August 2006, p. 5618-5625, Vol. 188, No. 15
0021-9193/06/$08.00+0     doi:10.1128/JB.00449-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Uropathogenic Escherichia coli Strains Generally Lack Functional Trg and Tap Chemoreceptors Found in the Majority of E. coli Strains Strictly Residing in the Gut

M. Chelsea Lane,1,2 Amanda L. Lloyd,2 Tiffany A. Markyvech,2 Erin C. Hagan,2 and Harry L. T. Mobley2*

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201,1 Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 481092

Received 31 March 2006/ Accepted 15 May 2006

The prevalence and function of four chemoreceptors, Tsr, Tar, Trg, and Tap, were determined for a collection of uropathogenic, fecal-commensal, and diarrheagenic Escherichia coli strains. tar and tsr were present or functional in nearly all isolates. However, trg and tap were significantly less prevalent or functional among the uropathogenic E. coli strains (both in 6% of strains) than among fecal-commensal strains (both in ≥50% of strains) or diarrheal strains (both in ≥75% of strains) (P < 0.02).


* Corresponding author. Mailing address: Department of Microbiology and Immunology, University of Michigan Medical School, 5641 Medical Science Building II, 1150 West Medical Center Drive, Ann Arbor, MI 48109. Phone: (734) 763-3531. Fax: (734) 764-3562. E-mail: hmobley{at}umich.edu.


Journal of Bacteriology, August 2006, p. 5618-5625, Vol. 188, No. 15
0021-9193/06/$08.00+0     doi:10.1128/JB.00449-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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