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Journal of Bacteriology, August 2006, p. 6016-6019, Vol. 188, No. 16
0021-9193/06/$08.00+0     doi:10.1128/JB.00330-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Analysis of the Terminus Region of the Caulobacter crescentus Chromosome and Identification of the dif Site

Rasmus B. Jensen*

Department of Life Sciences and Chemistry, Roskilde University, Universitetsvej 1, DK-4000 Roskilde, Denmark

Received 7 March 2006/ Accepted 8 June 2006

The terminus region of the Caulobacter crescentus chromosome and the dif chromosome dimer resolution site were characterized. The Caulobacter genome contains skewed sequences that abruptly switch strands at dif and may have roles in chromosome maintenance and segregation. Absence of dif or the XerCD recombinase results in a chromosome segregation defect. The Caulobacter terminus region is unusual, since it contains many essential or highly expressed genes.

* Corresponding author. Mailing address: Department of Life Sciences and Chemistry, Roskilde University, Universitetsvej 1, DK-4000 Roskilde, Denmark. Phone: 45 46742471. Fax: 45 46743011. E-mail: rbjensen{at}ruc.dk.

Journal of Bacteriology, August 2006, p. 6016-6019, Vol. 188, No. 16
0021-9193/06/$08.00+0     doi:10.1128/JB.00330-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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