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Journal of Bacteriology, September 2006, p. 6415-6418, Vol. 188, No. 17
0021-9193/06/$08.00+0     doi:10.1128/JB.00557-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Essential Role of Flavohemoglobin in Long-Term Anaerobic Survival of Bacillus subtilis

Michiko M. Nakano*

Department of Environmental and Biomolecular Systems, OGI School of Science and Engineering, Oregon Health and Science University, 20000 NW Walker Road, Beaverton, Oregon 97006

Received 19 April 2006/ Accepted 3 June 2006

A Bacillus subtilis culture incubated anaerobically in nitrate-containing medium lost viability during the first 3 days but recovered thereafter. A flavohemoglobin mutant showed very poor survival under these conditions unless the cells were prevented from carrying out nitrate respiration.

* Mailing address: Department of Environmental and Biomolecular Systems, OGI School of Science and Engineering, Oregon Health and Science University, 20000 NW Walker Road, Beaverton, OR 97006. Phone: (503) 748-4078. Fax: (503) 748-1464. E-mail: mnakano{at}ebs.ogi.edu.

Journal of Bacteriology, September 2006, p. 6415-6418, Vol. 188, No. 17
0021-9193/06/$08.00+0     doi:10.1128/JB.00557-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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