This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Kodgire, P. Articles by Rao, K. K. Search for Related Content PubMed PubMed Citation Articles by Kodgire, P. Articles by Rao, K. K.

 Previous Article  |  Next Article 

Journal of Bacteriology, September 2006, p. 6425-6428, Vol. 188, No. 17
0021-9193/06/$08.00+0     doi:10.1128/JB.00427-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

ScoC and SinR Negatively Regulate epr by Corepression in Bacillus subtilis

Prashant Kodgire, Madhulika Dixit, and K. Krishnamurthy Rao^*

School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India

Received 27 March 2006/ Accepted 16 June 2006

Negative regulation of epr in Bacillus subtilis 168 is mediated jointly by both ScoC and SinR, which bind to their respective target sites 62 bp apart. Increasing the distance between the two sites abolishes repression, indicating that the two proteins interact, thereby suggesting a mechanism of corepression.

Present address: Vascular Signalling Group, Institute of Cardiovascular Physiology, Johann Wolfgang Goethe University, 60590 Frankfurt am Main, Germany.