This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Grover, A.
Right arrow Articles by Sharma, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grover, A.
Right arrow Articles by Sharma, R.

 Previous Article

Journal of Bacteriology, October 2006, p. 7026-7032, Vol. 188, No. 19
0021-9193/06/$08.00+0     doi:10.1128/JB.00643-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Identification and Characterization of a Major Zn(II) Resistance Determinant of Mycobacterium smegmatis

Amit Grover and Rakesh Sharma*

Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India

Received 5 May 2006/ Accepted 18 July 2006

A zinc ion-sensitive mutant of Mycobacterium smegmatis was isolated. The transposon insertion was located in zitA (MSMEG0750), a gene coding for a cation diffusion facilitator family protein. Zinc ions specifically induced expression of zitA. In silico analysis revealed that environmental and opportunistic pathogenic species contain higher numbers of cation diffusion facilitator genes than do obligate pathogens.

* Corresponding author. Mailing address: Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110007, India. Phone: 91-11-27666156. Fax: 91-11-27667174. E-mail: rsharma{at}igib.res.in.

Journal of Bacteriology, October 2006, p. 7026-7032, Vol. 188, No. 19
0021-9193/06/$08.00+0     doi:10.1128/JB.00643-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»