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Journal of Bacteriology, February 2006, p. 1643-1647, Vol. 188, No. 4
0021-9193/06/$08.00+0 doi:10.1128/JB.188.4.1643-1647.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Anders S. Nilsson, and
Elisabeth Haggård-Ljungquist*
Department of Genetics, Microbiology and Toxicology, Stockholm University, S-106 91 Stockholm, Sweden
Received 1 September 2005/ Accepted 18 November 2005
The P2-like coliphages are highly similar; the structural genes show at least 96% identity. However, at two loci they have genes believed to be horizontally transferred. We show that the genetic content at the second loci, the TO region, contains six completely different sequences with high AT contents and with different open reading frames. The product of one of them exhibits reverse transcriptase activity and blocks infection of phage T5.
Present address: Isogenica Ltd., Babraham Hall, Babraham, Cambridge CB2 4AT, United Kingdom.
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