JB
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ferguson, G. P.
Right arrow Articles by Walker, G. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ferguson, G. P.
Right arrow Articles by Walker, G. C.

 Previous Article  |  Next Article 

Journal of Bacteriology, April 2006, p. 3143-3148, Vol. 188, No. 8
0021-9193/06/$08.00+0     doi:10.1128/JB.188.8.3143-3148.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

BacA-Mediated Bleomycin Sensitivity in Sinorhizobium meliloti Is Independent of the Unusual Lipid A Modification

Gail P. Ferguson,1* An Jansen,2 Victoria L. Marlow,1 and Graham C. Walker2*

Institute of Structural and Molecular Biology and Centre for Science at Extreme Conditions, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JR, United Kingdom,1 Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 021392

Received 25 October 2005/ Accepted 27 January 2006

Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

* Corresponding author. Mailing address for Graham C. Walker: Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139. Phone: (617) 253-7066. Fax: (617) 253-2643. E-mail: gwalker{at}mit.edu. Mailing address for Gail P. Ferguson: Institute of Structural and Molecular Biology and Centre for Science at Extreme Conditions, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JR, United Kingdom. Phone: 44 131 650 7066. Fax: 44 131 6501 3331. E-mail: G.Ferguson{at}ed.ac.uk.

Journal of Bacteriology, April 2006, p. 3143-3148, Vol. 188, No. 8
0021-9193/06/$08.00+0     doi:10.1128/JB.188.8.3143-3148.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
Mol. Cell. Biol. J. Virol. Microbiol. Mol. Biol. Rev.
ALL ASM JOURNALS

Copyright © 2006 by the American Society for Microbiology. All rights reserved.