Journal of Bacteriology, January 2007, p. 265-268, Vol. 189, No. 1
0021-9193/07/$08.00+0 doi:10.1128/JB.01124-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Molecular Evolution of the H-NS Protein: Interaction with Hha-Like Proteins Is Restricted to Enterobacteriaceae
Cristina Madrid,1
Jesús García,2
Miquel Pons,2 and
Antonio Juárez1*
Department of Microbiology, University of Barcelona, Avda. Diagonal 645, 08028 Barcelona, Spain,1
Laboratory of Biomolecular NMR, Institut de Recerca Biomèdica, Parc Cientific de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain2
Received 27 July 2006/
Accepted 25 September 2006
We show here that chromosomal hha-like genes are restricted to the Enterobacteriaceae. The H-NS N-terminal domain of members of this family includes an unaltered seven-amino-acid sequence located between helixes 1 and 2, termed the Hha signature, that contains key residues for H-NS-Hha interaction.
* Corresponding author. Mailing address: Department of Microbiology, University of Barcelona, Avda. Diagonal 645, 08028 Barcelona, Spain. Phone: 34934034624. Fax: 34934034629. E-mail: ajuarez{at}ub.edu.
Published ahead of print on 13 October 2006.
Journal of Bacteriology, January 2007, p. 265-268, Vol. 189, No. 1
0021-9193/07/$08.00+0 doi:10.1128/JB.01124-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
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Copyright © 2007 by the American Society for Microbiology. All rights reserved.