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Journal of Bacteriology, January 2007, p. 272-275, Vol. 189, No. 1
0021-9193/07/$08.00+0     doi:10.1128/JB.01387-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Proteolytic Adaptor for Transfer-Messenger RNA-Tagged Proteins from {alpha}-Proteobacteria{triangledown}

Faith H. Lessner, Bryan J. Venters, and Kenneth C. Keiler*

Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802

Received 30 August 2006/ Accepted 26 October 2006

We have identified an analog of SspB, the proteolytic adaptor for transfer-messenger RNA (tmRNA)-tagged proteins, in Caulobacter crescentus. C. crescentus SspB shares limited sequence similarity with Escherichia coli SspB but binds the tmRNA tag in vitro and is required for optimal proteolysis of tagged proteins in vivo.


* Corresponding author. Mailing address: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 401 Althouse Laboratory, University Park, PA 16802. Phone: (814) 863-0787. Fax: (814) 863-7024. E-mail: kkeiler{at}psu.edu.

{triangledown} Published ahead of print on 3 November 2006.


Journal of Bacteriology, January 2007, p. 272-275, Vol. 189, No. 1
0021-9193/07/$08.00+0     doi:10.1128/JB.01387-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




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