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Journal of Bacteriology, February 2007, p. 1468-1472, Vol. 189, No. 4
0021-9193/07/$08.00+0     doi:10.1128/JB.01174-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Competence-Dependent Bacteriocin Production by Streptococcus gordonii DL1 (Challis){triangledown}

Nicholas C. K. Heng,1,2* John R. Tagg,2 and Geoffrey R. Tompkins1*

Department of Oral Sciences,1 Department of Microbiology and Immunology, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand2

Received 30 July 2006/ Accepted 19 September 2006

The production of streptocins STH1 and STH2 by Streptococcus gordonii DL1 (Challis) is directly controlled by the competence regulon, which requires intact comR and comAB loci. The streptocin (sth) locus comprises two functional genes, sthA and sthB. Whereas STH1 activity requires sthA alone, STH2 activity depends on both genes.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand. Phone for N. C. K. Heng: 64 3 479-5155. Fax: 64 3 479-8540. E-mail: nicholas.heng{at}stonebow.otago.ac.nz. Phone for G. R. Tompkins: 64 3 479-5471. Fax: 64 3 479-7078. E-mail: geoffrey.tompkins{at}stonebow.otago.ac.nz.

{triangledown} Published ahead of print on 29 September 2006.

Journal of Bacteriology, February 2007, p. 1468-1472, Vol. 189, No. 4
0021-9193/07/$08.00+0     doi:10.1128/JB.01174-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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