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Svetlana N. Yurgel,1 and
Michael L. Kahn1,2*
Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164-6340,1 School of Molecular Biosciences, Washington State University, Pullman, Washington 99164-63402
Received 8 August 2006/ Accepted 28 November 2006
Nitrogen-fixing rhizobial bacteroids import dicarboxylates by using the DctA transporter. G114 of DctA is highly conserved. A G114D mutant is inactive, but DctA with a small amino acid (G114A) or a helix disrupter (G114P) retains significant activity. G114 probably interacts with other membrane helices in stabilizing a substrate-binding pocket.
Published ahead of print on 8 December 2006.
Present address: Department of Biology, University of Waterloo, 200 University Ave. W., Waterloo, ON N2L 3G1, Canada.
| Appl. Environ. Microbiol. | Infect. Immun. | Eukaryot. Cell |
|---|---|---|
| Mol. Cell. Biol. | J. Virol. | Microbiol. Mol. Biol. Rev. |
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