This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Devillard, E.
Right arrow Articles by Wallace, R. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Devillard, E.
Right arrow Articles by Wallace, R. J.

 Previous Article  |  Next Article 

Journal of Bacteriology, March 2007, p. 2566-2570, Vol. 189, No. 6
0021-9193/07/$08.00+0     doi:10.1128/JB.01359-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Metabolism of Linoleic Acid by Human Gut Bacteria: Different Routes for Biosynthesis of Conjugated Linoleic Acid{triangledown}

Estelle Devillard, Freda M. McIntosh, Sylvia H. Duncan, and R. John Wallace*

Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB, United Kingdom

Received 28 August 2006/ Accepted 26 December 2006

A survey of 30 representative strains of human gram-positive intestinal bacteria indicated that Roseburia species were among the most active in metabolizing linoleic acid (cis-9,cis-12-18:2). Different Roseburia spp. formed either vaccenic acid (trans-11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis-9,trans-11-18:2 in human tissues and the intestine, respectively.

* Corresponding author. Mailing address: Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB, United Kingdom. Phone: 44(0)1224-716656. Fax: 44(0)1224-716687. E-mail: john.wallace{at}rowett.ac.uk.

{triangledown} Published ahead of print on 5 January 2007.

Journal of Bacteriology, March 2007, p. 2566-2570, Vol. 189, No. 6
0021-9193/07/$08.00+0     doi:10.1128/JB.01359-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Liavonchanka, A., Rudolph, M. G., Tittmann, K., Hamberg, M., Feussner, I. (2009). On the Mechanism of a Polyunsaturated Fatty Acid Double Bond Isomerase from Propionibacterium acnes. J. Biol. Chem. 284: 8005-8012 [Abstract] [Full Text]  
  • Devillard, E., McIntosh, F. M., Paillard, D., Thomas, N. A., Shingfield, K. J., Wallace, R. J. (2009). Differences between human subjects in the composition of the faecal bacterial community and faecal metabolism of linoleic acid. Microbiology 155: 513-520 [Abstract] [Full Text]  
  • McIntosh, F. M., Shingfield, K. J., Devillard, E., Russell, W. R., Wallace, R. J. (2009). Mechanism of conjugated linoleic acid and vaccenic acid formation in human faecal suspensions and pure cultures of intestinal bacteria. Microbiology 155: 285-294 [Abstract] [Full Text]  
  • Mandalari, G., Nueno-Palop, C., Bisignano, G., Wickham, M. S. J., Narbad, A. (2008). Potential Prebiotic Properties of Almond (Amygdalus communis L.) Seeds. Appl. Environ. Microbiol. 74: 4264-4270 [Abstract] [Full Text]  
  • Wallace, R. J., McKain, N., Shingfield, K. J., Devillard, E. (2007). Isomers of conjugated linoleic acids are synthesized via different mechanisms in ruminal digesta and bacteria. J. Lipid Res. 48: 2247-2254 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»