This Article Full Text Full Text (PDF) Other Versions of this Article: JB.01921-06v1 189/7/2930    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Jervis, A. J. Articles by Green, J. Search for Related Content PubMed PubMed Citation Articles by Jervis, A. J. Articles by Green, J.

In Vivo Demonstration of FNR Dimers in Response to Lower O₂ Availability

Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom

Received 20 December 2006/ Accepted 20 January 2007

Escherichia coli FNR is an O₂-sensing transcription factor. In vitro studies indicate that anaerobic iron-sulfur cluster acquisition promotes FNR dimerization. Here, two-hybrid assays show that iron-sulfur cluster-dependent FNR dimers are formed in vivo in response to lower O₂ availability, consistent with the current model of FNR activation.

Published ahead of print on 2 February 2007.

This article has been cited by other articles:

• Partridge, J. D., Browning, D. F., Xu, M., Newnham, L. J., Scott, C., Roberts, R. E., Poole, R. K., Green, J. (2008). Characterization of the Escherichia coli K-12 ydhYVWXUT operon: regulation by FNR, NarL and NarP. Microbiology 154: 608-618 [Abstract] [Full Text]  
• Gaskell, A. A., Crack, J. C., Kelemen, G. H., Hutchings, M. I., Le Brun, N. E. (2007). RsmA Is an Anti-sigma Factor That Modulates Its Activity through a [2Fe-2S] Cluster Cofactor. J. Biol. Chem. 282: 31812-31820 [Abstract] [Full Text]