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Journal of Bacteriology, April 2007, p. 2933-2935, Vol. 189, No. 7
0021-9193/07/$08.00+0     doi:10.1128/JB.01619-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

DRS Is Far Less Divergent than Streptococcal Inhibitor of Complement of Group A Streptococcus{triangledown}

Vivek Sagar,1 Rajesh Kumar,2 Nirmal K. Ganguly,3 Thangam Menon,4 and Anuradha Chakraborti1*

Departments of Experimental Medicine and Biotechnology,1 Community Medicine, PGIMER, Chandigarh,2 ICMR, New Delhi,3 Department of Microbiology, University of Madras, Chennai, India4

Received 18 October 2006/ Accepted 11 January 2007

When 100 group A streptococcus isolates were screened, drs, a variant of sic, was identified in emm12 and emm55 isolates. Molecular characterization showed that the drs gene sequence is highly conserved, unlike the sic gene sequence. However, the variation in gene size observed was due to the presence of extra internal repeat sequences.

* Corresponding author. Mailing address: Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh, 160012 India. Phone: 91 172 2746277. Fax: 91 172 2744401. E-mail: superoxide{at}sify.com.

{triangledown} Published ahead of print on 19 January 2007.

Journal of Bacteriology, April 2007, p. 2933-2935, Vol. 189, No. 7
0021-9193/07/$08.00+0     doi:10.1128/JB.01619-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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