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Journal of Bacteriology, June 2008, p. 4084-4087, Vol. 190, No. 11
0021-9193/08/$08.00+0     doi:10.1128/JB.00065-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Mobilization of the incQ Plasmid R300B with a Chromosomal Conjugation System in Salmonella enterica Serovar Typhi {triangledown}

Stephen Baker,1,2* Derek Pickard,1 Sally Whitehead,1 Jeremy Farrar,2 and Gordon Dougan1

The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom,1 Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam2

Received 13 January 2008/ Accepted 27 March 2008

Salmonella pathogenicity island 7 (SPI-7) in Salmonella enterica serovar Typhi appears to be related to other genomic islands. Evidence suggests that SPI-7 is susceptible to spontaneous circularization, loss, and transposition. Here, we demonstrate that a region within SPI-7 has the ability to mobilize the small incQ plasmid R300B.

* Corresponding author. Mailing address: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam. Phone: (84-8) 9 241 761. Fax: (84-8) 9 238 904. E-mail: sbaker{at}oucru.org

{triangledown} Published ahead of print on 4 April 2008.

Journal of Bacteriology, June 2008, p. 4084-4087, Vol. 190, No. 11
0021-9193/08/$08.00+0     doi:10.1128/JB.00065-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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