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Journal of Bacteriology, August 2008, p. 5729-5732, Vol. 190, No. 16
0021-9193/08/$08.00+0     doi:10.1128/JB.00425-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

RadC, a Misleading Name?{triangledown} ,{dagger}

Laetitia Attaiech, Chantal Granadel, Jean-Pierre Claverys,* and Bernard Martin

Laboratoire de Microbiologie et Génétique Moléculaires, UMR 5100, CNRS, Université Paul Sabatier, Toulouse, France

Received 26 March 2008/ Accepted 5 June 2008

The pfam04002 annotation describes RadC as a bacterial DNA repair protein. Although the radC gene is expressed specifically during competence for genetic transformation in Streptococcus pneumoniae, we report that radC mutants exhibit normal uptake and processing of transforming DNA. They also display normal sensitivity to DNA-damaging agents, providing no support for the rad epithet.

* Corresponding author. Mailing address: Laboratoire de Microbiologie et Génétique Moléculaires, UMR 5100, CNRS, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 09, France. Phone: (33) 561-33-59-11. Fax: (33) 561-33-58-86. E-mail: claverys{at}ibcg.biotoul.fr

{triangledown} Published ahead of print on 13 June 2008.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

Journal of Bacteriology, August 2008, p. 5729-5732, Vol. 190, No. 16
0021-9193/08/$08.00+0     doi:10.1128/JB.00425-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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