Journal of Bacteriology, January 2008, p. 736-742, Vol. 190, No. 2
0021-9193/08/$08.00+0 doi:10.1128/JB.01559-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
Niche-Specific Features of the Intestinal Bacteroidales
,
Michael J. Coyne and
Laurie E. Comstock*
Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
Received 27 September 2007/
Accepted 28 October 2007
By analyzing the genomic sequences of 12 Bacteroidales species, we found that all intestinal species have numerous polysaccharide biosynthesis loci, many with promoters that we demonstrate undergo DNA inversion. This feature is not conserved in the Bacteroidales order as a whole, as oral species do not share these genetic features.
* Corresponding author. Mailing address: Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115. Phone: (617) 525-7822. Fax: (617) 264-5193. E-mail: lcomstock{at}rics.bwh.harvard.edu
Published ahead of print on 9 November 2007.
Supplemental material for this article may be found at http://jb.asm.org/.
Journal of Bacteriology, January 2008, p. 736-742, Vol. 190, No. 2
0021-9193/08/$08.00+0 doi:10.1128/JB.01559-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
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