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Journal of Bacteriology, October 2008, p. 6913-6917, Vol. 190, No. 20
0021-9193/08/$08.00+0     doi:10.1128/JB.00824-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Integrative Conjugative Elements and Related Elements Are Major Contributors to the Genome Diversity of Streptococcus agalactiae{triangledown} ,§

Mathieu Brochet,1 Elisabeth Couvé,1 Philippe Glaser,1 Gérard Guédon,2 and Sophie Payot2*

Unité de Génétique des Génomes Bactériens-URA CNRS2171, Institut Pasteur, 25-28 rue du Docteur Roux, 75724 Paris cedex 15, France,1 UMR1128 Génétique et Microbiologie, Nancy-Université, INRA, IFR110, Boulevard des Aiguillettes, B.P. 239, 54506 Vandœuvre-lès-Nancy, France2

Received 12 June 2008/ Accepted 4 August 2008

Thirty-five putative integrative conjugative elements and related elements were identified at 15 locations in the eight sequenced genomes of Streptococcus agalactiae. Twelve are composite, likely resulting from site-specific accretions. Circular forms were detected for five elements. Macroarray analysis confirmed their high plasticity and wide distribution in S. agalactiae.


* Corresponding author. Mailing address: UMR1128 Génétique et Microbiologie, Nancy-Université, INRA, IFR110, Boulevard des Aiguillettes, B.P. 239, 54506 Vandœuvre-lès-Nancy, France. Phone: 33 3 83 68 49 72. Fax: 33 3 83 68 44 99. E-mail: payot{at}nancy.inra.fr

{triangledown} Published ahead of print on 15 August 2008.

§ Supplemental material for this article may be found at http://jb.asm.org/.


Journal of Bacteriology, October 2008, p. 6913-6917, Vol. 190, No. 20
0021-9193/08/$08.00+0     doi:10.1128/JB.00824-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.







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