This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental material
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Barinova, N.
Right arrow Articles by Kulbachinskiy, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Barinova, N.
Right arrow Articles by Kulbachinskiy, A.

 Previous Article  |  Next Article 

Journal of Bacteriology, April 2008, p. 3088-3092, Vol. 190, No. 8
0021-9193/08/$08.00+0     doi:10.1128/JB.00008-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Lineage-Specific Amino Acid Substitutions in Region 2 of the RNA Polymerase {sigma} Subunit Affect the Temperature of Promoter Opening{triangledown} ,{dagger}

N. Barinova,1 E. Zhilina,1 I. Bass,1 V. Nikiforov,1,2 and A. Kulbachinskiy1*

Institute of Molecular Genetics, Kurchatov Sq. 2, Moscow 123182, Russia,1 Public Health Research Institute, 225 Warren Street, Newark, New Jersey 071032

Received 3 January 2008/ Accepted 5 February 2008

Highly conserved amino acid residues in region 2 of the RNA polymerase {sigma} subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.

* Corresponding author. Mailing address: Laboratory of Molecular Genetics of Microorganisms, Institute of Molecular Genetics, Kurchatov Sq. 2, Moscow 123182, Russia. Phone and fax: 7 (499) 1960015. E-mail: akulb{at}img.ras.ru

{triangledown} Published ahead of print on 15 February 2008.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

Journal of Bacteriology, April 2008, p. 3088-3092, Vol. 190, No. 8
0021-9193/08/$08.00+0     doi:10.1128/JB.00008-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»