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Subunit Affect the Temperature of Promoter Opening
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Institute of Molecular Genetics, Kurchatov Sq. 2, Moscow 123182, Russia,1 Public Health Research Institute, 225 Warren Street, Newark, New Jersey 071032
Received 3 January 2008/ Accepted 5 February 2008
Highly conserved amino acid residues in region 2 of the RNA polymerase
subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.
Published ahead of print on 15 February 2008.
Supplemental material for this article may be found at http://jb.asm.org/.
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