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Journal of Bacteriology, May 2008, p. 3404-3407, Vol. 190, No. 9
0021-9193/08/$08.00+0     doi:10.1128/JB.00040-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

The Legacy of HfrH: Mutations in the Two-Component System CreBC Are Responsible for the Unusual Phenotype of an Escherichia coli arcA Mutant{triangledown} ,{dagger}

Pablo I. Nikel,1,2,{ddagger} Alejandra de Almeida,1,{ddagger} M. Julia Pettinari,1 and Beatriz S. Méndez1*

Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires,1 Buenos Aires and Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, San Martín, Buenos Aires, Argentina2

Received 9 January 2008/ Accepted 25 February 2008

Strains derived from HfrH carrying the arcA2 null mutation exhibit a higher respiratory rate, enhanced glucose consumption, and a more-reduced intracellular redox state than arcA deletion mutants of a different lineage. The phenotype of the arcA2 mutants was due to the presence of a creC constitutive mutation introduced by P1 transduction.


* Corresponding author. Mailing address: Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Intendente Güiraldes 2160, C1428EGA, Buenos Aires, Argentina. Phone: 54-11-4576-3334. Fax: 54-11-4576-3342. E-mail: bea{at}qb.fcen.uba.ar

{triangledown} Published ahead of print on 7 March 2008.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

{ddagger} P.I.N. and A.D.A. contributed equally to this work.


Journal of Bacteriology, May 2008, p. 3404-3407, Vol. 190, No. 9
0021-9193/08/$08.00+0     doi:10.1128/JB.00040-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.







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