This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental material
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yang, M.
Right arrow Articles by Zhu, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yang, M.
Right arrow Articles by Zhu, J.

 Previous Article  |  Next Article 

Journal of Bacteriology, January 2009, p. 434-438, Vol. 191, No. 1
0021-9193/09/$08.00+0     doi:10.1128/JB.01247-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

The LuxR Family Quorum-Sensing Activator MrtR Requires Its Cognate Autoinducer for Dimerization and Activation but Not for Protein Folding{triangledown} ,§

Menghua Yang,1 Jennifer L. Giel,2 Tao Cai,1 Zengtao Zhong,3 and Jun Zhu1,2,3*

Department of Microbiology, MOA Key Lab of Microbiological Engineering of Agricultural Environment, Nanjing Agricultural University, Nanjing, China,1 Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania,2 The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China3

Received 6 September 2008/ Accepted 21 October 2008

MrtR, a LuxR homolog in Mesorhizobium tianshanense, is important for symbiosis. We found that MrtR requires its cognate N-acylhomoserine lactone for forming dimers, binding to a single DNA site and activating the downstream promoter. However, MrtR is able to fold independently of its ligand.

* Corresponding author. Mailing address: The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China. Phone and fax: 25-843-96645. E-mail: junzhu{at}nju.edu.cn

{triangledown} Published ahead of print on 31 October 2008.

§ Supplemental material for this article may be found at http://jb.asm.org/.

Journal of Bacteriology, January 2009, p. 434-438, Vol. 191, No. 1
0021-9193/09/$08.00+0     doi:10.1128/JB.01247-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»