This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Schué, M.
Right arrow Articles by Brown, N. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schué, M.
Right arrow Articles by Brown, N. L.

 Previous Article  |  Next Article 

Journal of Bacteriology, January 2009, p. 439-444, Vol. 191, No. 1
0021-9193/09/$08.00+0     doi:10.1128/JB.01063-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Sequence and Analysis of a Plasmid-Encoded Mercury Resistance Operon from Mycobacterium marinum Identifies MerH, a New Mercuric Ion Transporter{triangledown}

Mathieu Schué,1* Lynn G. Dover,1 Gurdyal. S. Besra,1 Julian Parkhill,2 and Nigel L. Brown1,§

School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom,1 The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom2

Received 30 July 2008/ Accepted 11 October 2008

In this study, we report the DNA sequence and biological analysis of a mycobacterial mercury resistance operon encoding a novel Hg2+ transporter. MerH was found to transport mercuric ions in Escherichia coli via a pair of essential cysteine residues but only when coexpressed with the mercuric reductase.

* Corresponding author. Present address: Institute for Structural Biology and Microbiology (IBSM), EIPL—CNRS UPR 9025, 31, Chemin Joseph Aiguier, 13402 Marseille, Cedex 20, France. Phone: 33 (0)4 91 16 42 22. Fax: 33 (0)4 91 71 58 57. E-mail: matschue{at}yahoo.fr

{triangledown} Published ahead of print on 17 October 2008.

§ Present address: College of Science and Engineering, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh EH9 3JY, United Kingdom.

Journal of Bacteriology, January 2009, p. 439-444, Vol. 191, No. 1
0021-9193/09/$08.00+0     doi:10.1128/JB.01063-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»